AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs
Dec 17, 2025 · 19:15
Natalie Serrino, cofounder of Gimlet Labs, presents how AI-generated kernels can automatically speed up custom PyTorch code by up to 24% on Apple M4 hardware using the Metal framework, with a 40% speedup from kernel fusion. The agentic system iterates through compilation, execution, correctness, and optimization, but faces challenges like validation of floating-point results and reliable benchmarking. Successes include rewriting average pool 1D as a convolution for 80% improvement, while failures occur on heavily optimized ops like matrix multiply. A real-world audio encoder model saw 70% faster inference on RTX 6000 Blackwell via six custom fused kernels. Serrino emphasizes that AI is best for rapidly searching optimizations and porting code to new hardware, not for surpassing human experts on novel algorithms.